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PhD student (f/m/x) for the study of microbial regulation of colorectal cancer development

Unternehmen

Universitätsmedizin Greifswald KöR (Job via XING.com)

Über diese Stelle

Greifswald
Promotion

Aufgaben

  • Design and perform experiments using mouse models of orthotopic colorectal cancer, including gnotobiotic mice
  • Work with primary human and murine intestinal organoids in 2D and 3D co-cultures to study host–microbial interactions
  • Perform and analyse scRNA/snRNA and spatial RNA sequencing
  • Conduct metagenomic sequencing and metabolomic studies to characterise microbiota and metabolites
  • Dissect microbiota-dependent pathways that regulate CRC progression, metastasis and age-dependent effects
  • Identify druggable host–microbial interactions that promote CRC progression
  • Collaborate in a cross-disciplinary research consortium and contribute to publications and presentations

Fähigkeiten

  • Master's degree (or equivalent) in Immunology, Microbiology, Molecular Biology, Biotechnology, Animal Science or related biological sciences
  • Ideally: experience working with mice (in vivo models)
  • Experience or basic skills in microbiology and cell culture techniques (organoids)
  • Familiarity or willingness to work with sequencing and omics approaches (scRNA/snRNA, spatial RNA-seq, metagenomics, metabolomics) is advantageous
  • Open-minded, active, team player
  • Good command of English (oral and written)

Benefits

  • Part-time position (65%) with fixed-term contract for 3 years (possibility of extension)
  • Payment according to TV-L (65% of E13)
  • Company pension schemes and employee discounts
  • Regular training and professional development programs
  • Interdisciplinary collaboration and research support (infrastructure and resources)
  • Flexible working hours and health promotion programs (cooperation with Hansefit GmbH)
  • Family office support for accommodation and work–life balance
  • Located in Greifswald — attractive university town near the Baltic Sea

Standort

Adresse

17475 Greifswald, Deutschland


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